Computational methods in noncoding RNA research
نویسندگان
چکیده
منابع مشابه
Computational Genomics of Noncoding RNA Genes
The number of known noncoding RNA genes is expanding rapidly. Computational analysis of genome sequences, which has been revolutionary for protein gene analysis, should also be able to address questions of the number and diversity of noncoding RNA genes. However, noncoding RNAs present computational genomics with a new set of challenges.
متن کاملComputational Identification of Noncoding RNA Genes through Phylogenetic Shadowing
Although fairly accurate databases exist for protein-coding genes, little is known about another important class of genes known as noncoding RNA genes. These genes, which have been implicated in a wide variety of critical biochemical pathways including brain development [7] and viral defense [5], are not translated into polypeptides. Instead, their transcribed RNAs fold into stable, base-paired...
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Introduction: Breast cancer is the second most common cause of cancer-related death among females, which requires an exploration for markers to propose a more specific categorization of this cancer. Long noncoding RNAs (lncRNAs), the main subset of noncoding transcripts, are involved in tumorigenic processes. In this study, we investigated the expression of the fer-1–like family member 4 (FER...
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ژورنال
عنوان ژورنال: Journal of Mathematical Biology
سال: 2007
ISSN: 0303-6812,1432-1416
DOI: 10.1007/s00285-007-0122-6